Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Novel insecticidal proteins from ferns resemble insecticidal proteins from Bacillus thuringiensis.

Wei, Jun-Zhi; Lum, Amy; Schepers, Eric; Liu, Lu; Weston, Ross T; McGinness, Bruce S; Heckert, Matthew J; Xie, Weiping; Kassa, Adane; Bruck, Denny; Rauscher, Gilda; Kapka-Kitzman, Deirdre; Mathis, John P; Zhao, Jian-Zhou; Sethi, Amit; Barry, Jennifer; Lu, Albert L; Brugliera, Filippa; Lee, Eunice L; van derWeerden, Nicole L; Eswar, Narayanan; Maher, Megan J; Anderson, Marilyn A.

Proc Natl Acad Sci U S A ; 120(44): e2306177120, 2023 Oct 31.

Artigo em Inglês | MEDLINE | ID: mdl-37871210

2.

Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV.

Anderson, Alexander J; Crameri, Jordan J; Ang, Ching-Seng; Malcolm, Tess R; Kang, Yilin; Baker, Megan J; Palmer, Catherine S; Sharpe, Alice J; Formosa, Luke E; Ganio, Katherine; Baker, Michael J; McDevitt, Christopher A; Ryan, Michael T; Maher, Megan J; Stojanovski, Diana.

EMBO Rep ; 24(8): e56430, 2023 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-37272231

3.

Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly.

Formosa, Luke E; Maghool, Shadi; Sharpe, Alice J; Reljic, Boris; Muellner-Wong, Linden; Stroud, David A; Ryan, Michael T; Maher, Megan J.

Proc Natl Acad Sci U S A ; 119(9)2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-35210360

4.

Biochemical Characterization of Caenorhabditis elegans Ferritins.

Mubarak, Sanjeedha S M; Malcolm, Tess R; Brown, Hamish G; Hanssen, Eric; Maher, Megan J; McColl, Gawain; Jameson, Guy N L.

Biochemistry ; 62(9): 1484-1496, 2023 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-37014173

5.

Structural and Functional Investigation of the Periplasmic Arsenate-Binding Protein ArrX from Chrysiogenes arsenatis.

Poddar, Nilakhi; Badilla, Consuelo; Maghool, Shadi; Osborne, Thomas H; Santini, Joanne M; Maher, Megan J.

Biochemistry ; 60(6): 465-476, 2021 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-33538578

6.

Crystal structure of bacterial succinate:quinone oxidoreductase flavoprotein SdhA in complex with its assembly factor SdhE.

Maher, Megan J; Herath, Anuradha S; Udagedara, Saumya R; Dougan, David A; Truscott, Kaye N.

Proc Natl Acad Sci U S A ; 115(12): 2982-2987, 2018 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-29514959

7.

What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both?

Maghool, Shadi; Ryan, Michael T; Maher, Megan J.

Int J Mol Sci ; 21(19)2020 Sep 23.

Artigo em Inglês | MEDLINE | ID: mdl-32977416

8.

The purification of the σ^FpvI/FpvR₂₀ and σ^PvdS/FpvR₂₀ protein complexes is facilitated at room temperature.

Casas Garcia, G Patricia; Perugini, Matthew A; Lamont, Iain L; Maher, Megan J.

Protein Expr Purif ; 160: 11-18, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-30878602

9.

The central active site arginine in sulfite oxidizing enzymes alters kinetic properties by controlling electron transfer and redox interactions.

Hsiao, Ju-Chun; McGrath, Aaron P; Kielmann, Linda; Kalimuthu, Palraj; Darain, Farzana; Bernhardt, Paul V; Harmer, Jeffrey; Lee, Mihwa; Meyers, Kimberley; Maher, Megan J; Kappler, Ulrike.

Biochim Biophys Acta Bioenerg ; 1859(1): 19-27, 2018 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-28986298

10.

Integrated activities of two alternative sigma factors coordinate iron acquisition and uptake by Pseudomonas aeruginosa.

Edgar, Rebecca J; Hampton, Georgina E; Garcia, G Patricia Casas; Maher, Megan J; Perugini, Matthew A; Ackerley, David F; Lamont, Iain L.

Mol Microbiol ; 106(6): 891-904, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28971540

11.

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2.

Stroud, David A; Maher, Megan J; Lindau, Caroline; Vögtle, F-Nora; Frazier, Ann E; Surgenor, Elliot; Mountford, Hayley; Singh, Abeer P; Bonas, Matteo; Oeljeklaus, Silke; Warscheid, Bettina; Meisinger, Chris; Thorburn, David R; Ryan, Michael T.

Hum Mol Genet ; 24(19): 5404-15, 2015 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-26160915

12.

The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates.

Iwata, Momi; Lee, Yang; Yamashita, Tetsuo; Yagi, Takao; Iwata, So; Cameron, Alexander D; Maher, Megan J.

Proc Natl Acad Sci U S A ; 109(38): 15247-52, 2012 Sep 18.

Artigo em Inglês | MEDLINE | ID: mdl-22949654

13.

A GTPase chimera illustrates an uncoupled nucleotide affinity and release rate, providing insight into the activation mechanism.

Guilfoyle, Amy P; Deshpande, Chandrika N; Font Sadurni, Josep; Ash, Miriam-Rose; Tourle, Samuel; Schenk, Gerhard; Maher, Megan J; Jormakka, Mika.

Biophys J ; 107(12): L45-L48, 2014 Dec 16.

Artigo em Inglês | MEDLINE | ID: mdl-25517170

14.

The bacterial SoxAX cytochromes.

Kappler, Ulrike; Maher, Megan J.

Cell Mol Life Sci ; 70(6): 977-92, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-22907414

15.

Structural basis of GDP release and gating in G protein coupled Fe2+ transport.

Guilfoyle, Amy; Maher, Megan J; Rapp, Mikaela; Clarke, Ronald; Harrop, Stephen; Jormakka, Mika.

EMBO J ; 28(17): 2677-85, 2009 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-19629046

16.

Crystal structure of A3B3 complex of V-ATPase from Thermus thermophilus.

Maher, Megan J; Akimoto, Satoru; Iwata, Momi; Nagata, Koji; Hori, Yoshiko; Yoshida, Masasuke; Yokoyama, Shigeyuki; Iwata, So; Yokoyama, Ken.

EMBO J ; 28(23): 3771-9, 2009 Dec 02.

Artigo em Inglês | MEDLINE | ID: mdl-19893485

17.

Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer.

Deshpande, Chandrika N; McGrath, Aaron P; Font, Josep; Guilfoyle, Amy P; Maher, Megan J; Jormakka, Mika.

Acta Crystallogr Sect F Struct Biol Cryst Commun ; 69(Pt 4): 399-404, 2013 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-23545645

18.

The structure of the complex between the arsenite oxidase from Pseudorhizobium banfieldiae sp. strain NT-26 and its native electron acceptor cytochrome c₅₅₂.

Poddar, Nilakhi; Santini, Joanne M; Maher, Megan J.

Acta Crystallogr D Struct Biol ; 79(Pt 4): 345-352, 2023 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-36995233

19.

Insights into structure and function of the active site of SoxAX cytochromes.

Kilmartin, James R; Maher, Megan J; Krusong, Kuakarun; Noble, Christopher J; Hanson, Graeme R; Bernhardt, Paul V; Riley, Mark J; Kappler, Ulrike.

J Biol Chem ; 286(28): 24872-81, 2011 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-21592966

20.

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.

Brazel, Erin B; Tan, Aimee; Neville, Stephanie L; Iverson, Amy R; Udagedara, Saumya R; Cunningham, Bliss A; Sikanyika, Mwilye; De Oliveira, David M P; Keller, Bernhard; Bohlmann, Lisa; El-Deeb, Ibrahim M; Ganio, Katherine; Eijkelkamp, Bart A; McEwan, Alastair G; von Itzstein, Mark; Maher, Megan J; Walker, Mark J; Rosch, Jason W; McDevitt, Christopher A.

Cell Rep ; 38(2): 110202, 2022 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-35021083

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